Work-life balance of dual-earner couples: Do advantages and disadvantages of workplace demands and resources accumulate within partnerships?

Pausch S, Reimann M, Abendroth A, Diewald M. Work-life balance of dual-earner couples: Do advantages and disadvantages of workplace demands and resources accumulate within partnerships?. SFB 882 Working Paper Series. Vol 54. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2015.This study investigates the complex interplay between couples’ work and private life spheres and disentangles how demands and resources affect partners’ satisfaction with their work-life balance. Next to the individual process of spillover of workplace demands and resources to the private life sphere we investigate processes of crossover of one spouse’s demands and resources to the other. We particularly argue that within partnerships an accumulation of individual demands and resources from both partners takes place leading to specifically disadvantaged situations, when it comes to demands, and specifically advantaged situations, when it comes to resources. Furthermore we investigate gender differences in the relevance of spillover, crossover and accumulation for a satisfying work-life balance. We make use of a German Linked Employer-Employee Panel Survey (LEEP-B3), which includes information on 100 work organizations, 6,454 employees, and their partners (2,185). Our results mainly support the spillover of demands and resources from work to private life meaning that workplace demands make integrating work and private life more difficult whereas workplace resources can help reaching a satisfying work-life balance more easily. The results also partly support the hypothesized crossover of demands and resources from one partner to the other. However, there is no such clear-cut picture for the accumulation of demands and resources within partnerships

Work-life balance of dual-earner couples: Do advantages and disadvantages of workplace demands and resources accumulate within partnerships?

Pausch S, Reimann M, Abendroth A, Diewald M. Work-life balance of dual-earner couples: Do advantages and disadvantages of workplace demands and resources accumulate within partnerships?. SFB 882 Working Paper Series. Vol 54. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2015.This study investigates the complex interplay between couples’ work and private life spheres and disentangles how demands and resources affect partners’ satisfaction with their work-life balance. Next to the individual process of spillover of workplace demands and resources to the private life sphere we investigate processes of crossover of one spouse’s demands and resources to the other. We particularly argue that within partnerships an accumulation of individual demands and resources from both partners takes place leading to specifically disadvantaged situations, when it comes to demands, and specifically advantaged situations, when it comes to resources. Furthermore we investigate gender differences in the relevance of spillover, crossover and accumulation for a satisfying work-life balance. We make use of a German Linked Employer-Employee Panel Survey (LEEP-B3), which includes information on 100 work organizations, 6,454 employees, and their partners (2,185). Our results mainly support the spillover of demands and resources from work to private life meaning that workplace demands make integrating work and private life more difficult whereas workplace resources can help reaching a satisfying work-life balance more easily. The results also partly support the hypothesized crossover of demands and resources from one partner to the other. However, there is no such clear-cut picture for the accumulation of demands and resources within partnerships

Employee and partner surveys wave 3 of the Linked-Employer-Employee-Panel (LEEP-B3) Project (DFG – 373090005): Organizational Inequalities and Interdependencies between Capabilities in Work and Personal Life: A Study of Employees in Different Work Organizations. Technical Report

Marx C, Abendroth A, Bächmann A-C, et al. Employee and partner surveys wave 3 of the Linked-Employer-Employee-Panel (LEEP-B3) Project (DFG – 373090005): Organizational Inequalities and Interdependencies between Capabilities in Work and Personal Life: A Study of Employees in Different Work Organizations. Technical Report. Bielefeld: Univ., Fak. für Soziologie; 2020

Increased Immunosignals of Collagen IV and Fibronectin Indicate Ischemic Consequences for the Neurovascular Matrix Adhesion Zone in Various Animal Models and Human Stroke Tissue

Ischemic stroke causes cellular alterations in the "neurovascular unit" (NVU) comprising neurons, glia, and the vasculature, and affects the blood-brain barrier (BBB) with adjacent extracellular matrix (ECM). Limited data are available for the zone between the NVU and ECM that has not yet considered for neuroprotective approaches. This study describes ischemia-induced alterations for two main components of the neurovascular matrix adhesion zone (NMZ), i.e., collagen IV as basement membrane constituent and fibronectin as crucial part of the ECM, in conjunction with traditional NVU elements. For spatio-temporal characterization of these structures, multiple immunofluorescence labeling was applied to tissues affected by focal cerebral ischemia using a filament-based model in mice (4, 24, and 72 h of ischemia), a thromboembolic model in rats (24 h of ischemia), a coagulation-based model in sheep (2 weeks of ischemia), and human autoptic stroke tissue (3 weeks of ischemia). An increased fibronectin immunofluorescence signal demarcated ischemia-affected areas in mice, along with an increased collagen IV signal and BBB impairment indicated by serum albumin extravasation. Quantifications revealed a region-specific pattern with highest collagen IV and fibronectin intensities in most severely affected neocortical areas, followed by a gradual decline toward the border zone and non-affected regions. Comparing 4 and 24 h of ischemia, the subcortical fibronectin signal increased significantly over time, whereas neocortical areas displayed only a gradual increase. Qualitative analyses confirmed increased fibronectin and collagen IV signals in ischemic areas from all tissues and time points investigated. While the increased collagen IV signal was restricted to vessels, fibronectin appeared diffusely arranged in the parenchyma with focal accumulations associated to the vasculature. Integrin alpha(5) appeared enriched in the vicinity of fibronectin and vascular elements, while most of the non-vascular NVU elements showed complementary staining patterns referring to fibronectin. This spatio-temporal characterization of ischemia-related alterations of collagen IV and fibronectin in various stroke models and human autoptic tissue shows that ischemic consequences are not limited to traditional NVU components and the ECM, but also involve the NMZ. Future research should explore more components and the pathophysiological properties of the NMZ as a possible target for novel neuroprotective approaches

Methodenbericht Faktorieller Survey (Vignetten) Projekt B3 „Wechselwirkungen zwischen Verwirklichungschancen im Berufs- und Privatleben“

Reimann M, Andernach B, Schunck R, et al. Methodenbericht Faktorieller Survey (Vignetten) Projekt B3 „Wechselwirkungen zwischen Verwirklichungschancen im Berufs- und Privatleben“. SFB 882 Technical Report Series. Vol 9. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2014

Technical Report Factorial Survey (Vignettes) Wave 1: Project B3 “Interactions Between Capabilities in Work and Private Life”

Reimann M, Andernach B, Schunck R, et al. Technical Report Factorial Survey (Vignettes) Wave 1: Project B3 “Interactions Between Capabilities in Work and Private Life”. SFB 882 Technical Report Series. Vol 20. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2015

Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades

Intervertebral disc (IVD) herniation and degeneration is a major source of back pain. In order to regenerate a herniated and degenerated disc, closure of the anulus fibrosus (AF) is of crucial importance. For molecular characterization of AF, genome-wide Affymetrix HG-U133plus2.0 microarrays of native AF and cultured cells were investigated. To evaluate if cells derived from degenerated AF are able to initiate gene expression of a regenerative pattern of extracellular matrix (ECM) molecules, cultivated cells were stimulated with bone morphogenetic protein 2 (BMP2), transforming growth factor β1 (TGFβ1) or tumor necrosis factor-α (TNFα) for 24 h. Comparative microarray analysis of native AF tissues showed 788 genes with a significantly different gene expression with 213 genes more highly expressed in mild and 575 genes in severe degenerated AF tissue. Mild degenerated native AF tissues showed a higher gene expression of common cartilage ECM genes, whereas severe degenerated AF tissues expressed genes known from degenerative processes, including matrix metalloproteinases (MMP) and bone associated genes. During monolayer cultivation, only 164 differentially expressed genes were found. The cells dedifferentiated and altered their gene expression profile. RTD-PCR analyses of BMP2- and TGFβ1-stimulated cells from mild and severe degenerated AF tissue after 24 h showed an increased expression of cartilage associated genes. TNFα stimulation increased MMP1, 3, and 13 expression. Cells derived from mild and severe degenerated tissues could be stimulated to a comparable extent. These results give hope that regeneration of mildly but also strongly degenerated disc tissue is possible

Интеллектуальные энергосистемы. Т. 3

Настоящий сборник содержит материалы V Международного молодежного форума «Интеллектуальные энергосистемы», проведенного 9 - 13 октября 2017г. на базе Энергетического института Томского политехнического университета

Technical report employer survey wave 2: Project B3 "Interactions Between Capabilities in Work and Private Life"

Reimann M, Pausch S, Diewald M, et al. Technical report employer survey wave 2: Project B3 "Interactions Between Capabilities in Work and Private Life". SFB 882 Technical Report Series. Vol 19. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2015

Verknüpfung der LEEP-B3 Befragungsdaten mit administrativen IAB-Daten

Jacobebbinghaus P, Seth S, Diewald M, et al. Verknüpfung der LEEP-B3 Befragungsdaten mit administrativen IAB-Daten. SFB 882 Technical Report Series. Vol 14. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2014